The Evolution of HRT: From Static Dosing to Physiologic Restoration

Increase clinical outcomes and satisfaction for your patients
Join Harbor Academy for an advanced clinical training on Physiologic Hormone Restoration Therapy (PHRT). Move beyond "symptom management" and learn to mimic the body's natural rhythmic cycles for systemic health.

Is "Low Dose Static" Enough for Your Patients?

As prescribers, we are often taught that the goal of HRT is simply to ameliorate vasomotor symptoms like hot flashes and night sweats. But current literature suggests we are missing the bigger picture.

• The "Dose Ceiling": Static dosing avoids endometrial buildup but often fails to provide enough estrogen for true heart, bone, and brain protection.
• The Systemic Gap: Patients may find relief from hot flashes but still struggle with brain fog, joint pain, sleep issues, and lipid regulation.

There is a better way. Physiologic HRT (PHRT) uses rhythmic dosing to restore natural hormonal peaks—specifically the Day 12 Estradiol Peak—to elicit progesterone receptors and protect the uterine lining without sacrificing systemic benefits.

Webinar Agenda: Implementation & Logistics
In this comprehensive 2-hour session, we will cover:

1. Introduction to Rhythmic Hormones
   ○ Review of The Danish Heart Study (n=700,000) and cardiovascular endpoints.
   ○ The difference between "Static" vs. "Rhythmic" curves.
   ○ Why timing matters: How avoiding early Testosterone initiation protects Estrogen Receptor signaling.
   Implementation in Patients
   ○ Who is a candidate? Protocols for
2. Menopause, Perimenopause, POI/POF, and PCOS.
   ○ PHRT vs. Wiley Protocol: How PHRT adjusts the estradiol peak and provides a slower transition to reduce side effects like breast tenderness and fluid retention.
3. Logistics of Writing Prescriptions
   ○ How to transition patients from standard HRT to Rhythmic Dosing.
   ○ Exact dosing guidelines to ensure uterine safety.
   ○ How to join the Women’s Hormone Network (WHN) and get listed as a provider.

Why Prescribers Trust Harbor Compounding

We know that "compounding" can raise questions about consistency. Harbor Compounding, a WHN Member Pharmacy, adheres to the strictest quality standards to ensure your patient's clinical outcome matches your prescription.

Potency Testing for EVERY Batch:
We test every single batch of Physiologic HRT creams to ensure precise dosing.

Optimum Absorption (<50 Microns):
We perform particle size testing for EVERY estradiol, progesterone, and testosterone powder. We ensure a particle size of less than 50 microns for optimum transdermal absorption11.

National Reach:
Licensed in 45+ states to support your practice wherever you are located.

Meet Your Instructor

Dr. Yun-Ching Chen
Internal Medicine Physician
Dr. Chen is a pioneer in Physiologic HRT, having started with the Wiley Protocol in the early 2000s. She specializes in customizing rhythmic protocols to the individual patient, moving beyond standardized approaches to solve complex cases.
She will be leading this session to help you bridge the gap between standard guidelines and optimal restoration.

Ready to maximize your patient outcomes?

Don't let your patients settle for "just enough" hormone therapy. Give them the restoration they need with a scientifically backed, rhythmically dosed protocol.

Limited spots available for
the Feb 24th Live Session.
Do you have questions?
Email us at
[email protected].